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Fabrice Jaffré Selected Research

SB 215505

8/2008Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice.
8/2004Involvement of the serotonin 5-HT2B receptor in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production by ventricular fibroblasts.

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Fabrice Jaffré Research Topics

Disease

6Cardiomegaly (Heart Hypertrophy)
10/2014 - 07/2003
5Hypertrophy
10/2014 - 07/2003
3Heart Failure
10/2014 - 01/2009
2COVID-19
11/2020 - 01/2020
2Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
01/2019 - 07/2003
2Hypertension (High Blood Pressure)
08/2008 - 01/2004
1Ventricular Tachycardia
10/2020
1Polymorphic catecholergic ventricular tachycardia
10/2020
1Noonan Syndrome (Female Pseudo-Turner Syndrome)
01/2019
1Heart Diseases (Heart Disease)
01/2015
1Reperfusion Injury
10/2014
1Fibrosis (Cirrhosis)
10/2014
1Inflammation (Inflammations)
05/2011
1Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
01/2009
1Body Weight (Weight, Body)
08/2008
1Pulmonary Hypertension
01/2004
1Hypoxia (Hypoxemia)
01/2004
1Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
07/2003

Drug/Important Bio-Agent (IBA)

4Serotonin (5 Hydroxytryptamine)IBA
01/2009 - 07/2003
3CytokinesIBA
01/2009 - 08/2004
3Isoproterenol (Isoprenaline)FDA LinkGeneric
01/2009 - 08/2004
35-HT2B Serotonin ReceptorIBA
08/2004 - 07/2003
2SB 215505IBA
08/2008 - 08/2004
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2008 - 08/2004
1RNA (Ribonucleic Acid)IBA
11/2020
1Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
10/2020
1ChemokinesIBA
01/2020
1Phosphotransferases (Kinase)IBA
01/2019
1MAP Kinase Kinase 1IBA
01/2019
1Serum Response FactorIBA
10/2014
1Transcription Factors (Transcription Factor)IBA
10/2014
1TAC AlternateIBA
10/2014
1GuanosineIBA
10/2014
1myocardinIBA
10/2014
1Matrix Metalloproteinases (MMPs)IBA
06/2012
1Adrenergic Receptors (Adrenergic Receptor)IBA
06/2012
1ApolipoproteinsIBA
05/2011
1Cyclophilin AIBA
05/2011
1Apolipoproteins E (ApoE)IBA
05/2011
1Adrenergic Agents (Adrenergic Drugs)IBA
01/2009
1Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2009
1Angiotensin Receptors (Angiotensin II Receptor)IBA
01/2009
1AngiotensinsIBA
01/2009
1Adrenergic Agonists (Adrenergic Receptor Agonist)IBA
01/2009
1NADPH Oxidases (NAD(P)H oxidase)IBA
08/2008
14- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA
08/2008
1Angiotensin IIIBA
08/2008
1NADP (NADPH)IBA
08/2008
1Superoxides (Superoxide)IBA
08/2008
1Reactive Oxygen Species (Oxygen Radicals)IBA
08/2008
1SB 206553IBA
08/2004
1Interleukin-6 (Interleukin 6)IBA
08/2004
1Interleukin-1beta (Interleukin 1 beta)IBA
08/2004
1Atrial Natriuretic Factor (ANF)IBA
07/2003
1Myosin Heavy Chains (Myosin Heavy Chain)IBA
07/2003

Therapy/Procedure

2Therapeutics
01/2015 - 01/2009